About OpenBiology
Our Mission
OpenBiology is dedicated to advancing agricultural biotechnology through accessible, expert-driven genome editing solutions. We empower crop researchers, plant breeders, and agricultural scientists with cutting-edge computational tools and professional services for designing guide RNAs and implementing CRISPR-based genome editing in crops. Our mission is to democratize precision breeding technology and accelerate crop improvement for global food security.
About openbiology
gRNA Design & Optimization Service
Demand-Based Statistical & Bioinformatics Analysis
Mutation detection from Sanger Sequencing files
Our specialized gRNA design service delivers computational analysis and guide RNA sequence design for your genome editing projects in crops. We perform comprehensive in silico design using state-of-the-art algorithms to identify optimal gRNA sequences targeting your genes of interest in major crop species. Our service includes off-target
Our specialized gRNA design service delivers computational analysis and guide RNA sequence design for your genome editing projects in crops. We perform comprehensive in silico design using state-of-the-art algorithms to identify optimal gRNA sequences targeting your genes of interest in major crop species. Our service includes off-target analysis, efficacy prediction, and optimization for your specific experimental approach (CRISPR/Cas9, base editing, or prime editing). We provide detailed reports with ranked gRNA candidates, design rationale, and implementation recommendations.
Note: Our service provides gRNA sequence designs and recommendations only. We do not provide synthesis or oligonucleotide (oligo) synthesis services. Clients are responsible for synthesizing the designed gRNAs through commercial vendors or their own laboratory facilities
Mutation detection from Sanger Sequencing files
Demand-Based Statistical & Bioinformatics Analysis
Mutation detection from Sanger Sequencing files
We provide comprehensive analysis of Sanger sequencing data to identify and characterize mutations resulting from your genome editing experiments. Our service processes your sequencing chromatogram files (.ab1 or .seq) to detect insertions, deletions, substitutions, and other genetic variations in your edited crop lines. We deliver detai
We provide comprehensive analysis of Sanger sequencing data to identify and characterize mutations resulting from your genome editing experiments. Our service processes your sequencing chromatogram files (.ab1 or .seq) to detect insertions, deletions, substitutions, and other genetic variations in your edited crop lines. We deliver detailed mutation reports including mutation type, position, zygosity status, and potential functional impact. This service is essential for validating successful genome edits and confirming the absence of off-target mutations in screened regions.
Demand-Based Statistical & Bioinformatics Analysis
Demand-Based Statistical & Bioinformatics Analysis
Demand-Based Statistical & Bioinformatics Analysis
We provide customized statistical and bioinformatics analysis tailored to your research needs and experimental data. Our analysis services include parametric and non-parametric statistical tests (ANOVA, t-tests), multivariate analysis techniques (Principal Component Analysis, cluster analysis, correlation analysis), and advanced data vis
We provide customized statistical and bioinformatics analysis tailored to your research needs and experimental data. Our analysis services include parametric and non-parametric statistical tests (ANOVA, t-tests), multivariate analysis techniques (Principal Component Analysis, cluster analysis, correlation analysis), and advanced data visualization. We help you extract meaningful patterns from your experimental datasets, assess statistical significance, and interpret complex biological relationships in your crop genome editing studies.